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SYSTEM, METHOD AND APPARATUS FOR RAPID BRIEF FEEDBACK INTRACEREBRAL STIMULATION BASED ON REAL-TIME DESYNCHRONIZATION

申请公布号:US2016361546(A1)

申请号:US201615177615

申请日期:2016.06.09

申请公布日期:2016.12.15

申请人:
THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO ;THE HOSPITAL FOR SICK CHILDREN

发明人:SALAM Muhammad Tariqus;GENOV Roman;PEREZ-VELAZQUEZ Jose Luis

分类号:A61N1/36;A61B5/00;A61B5/04;A61B5/0478

主分类号:A61N1/36

地址:Toronto CA

摘要:Systems, methods and apparatuses described herein generally provide a system, methods and apparatuses for stopping the development of paroxysms based on a feedback stimulation at low frequencies for a few seconds after the detection of a seizure precursor.

主权项:1. A method of monitoring, detecting and stimulating a human patient with epilepsy, said method comprising: monitoring said patient for a seizure onset by real-time intracranial EEG (icEEG) microelectrodes coupled to two hippocampi of the patient; detecting said seizure onset using phase synchronization analysis; and stimulating a hippocampus (seizure origination) of the patient upon detection of a seizure onset by said sensed icEEG of said hippocampi.

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