Caspofungin acetate formulations

申请公布号：US9636407(B2)

申请号：US201213724266

申请日期：2012.12.21

申请公布日期：2017.05.02

申请人：

FRESENIUS KABI USA, LLC

发明人：Jiang John Zhiqiang;Usayapant Arunya;Bowman David;Kwok Keith;Peterson Joel

分类号：A61K31/198;A61K47/18;A61K38/12;A61K9/19;A61K9/00

主分类号：A61K31/198

代理机构：

Pitts & Lake, P.C.

代理人：Pitts & Lake, P.C.

地址：Lake Zurich IL US

摘要：A caspofungin composition includes caspofungin acetate and at least one amino acid, where the composition is a solid. The solid composition may be made by forming a liquid mixture including a solvent, caspofungin acetate and the amino acid(s), and lyophilizing the liquid mixture.

主权项：1. A composition, comprising: from 10 to 150 mg of caspofungin acetate, and arginine, where the mass ratio of the arginine to caspofungin acetate is from 1:1 to 3:1; where the composition is a solid.

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OPTICAL INFORMATION READER