derivados do isoxazol [4,5] piridin-3-il-piperazina, seu processo de preparação, seu medicamento e seu uso

申请公布号：BRPI0919342(A2)

申请号：BR2009PI19342

申请日期：2009.09.15

申请公布日期：2015.12.29

申请人：

F.HOFFMANN LA ROCHE AG

发明人：GEORGE JAESCHKE;LUCA GOBBI;LUCINDA STEWARD;ROSA MARIA RODRIGUEZ SARMIENTO

分类号：C07D498/04;A61K31/437;A61P25/30

主分类号：C07D498/04

摘要：The present invention provides compounds of formula I, having affinity and selectivity for the dopamine D3 receptors, their manufacture, pharmaceutical compositions containing them and their use for the therapeutic and/or prophylactic treatment of cognitive disorders.

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Instrument to stretch the jaw is wood tongs, to be inserted into the mouth and spread apart to force the jaw open and exercise the jaw muscles

Method for integrating an optical indicator during interchange of poles in shockproof plugs allows the correct connection of a phase and a neutral wire to be checked during the connection of shockproof plugs to a mains wall outlet.

Dissemination of product information has data processed and relayed to unit coupled to the Internet

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Verfahren zum Versenden von Zugangsdaten an eine insbesondere in einem Kraftfahrzeug befindliche Teilnehmerstation für eine spezielle Zugangsart zu einer Dienstleisterstation

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Using mobile telephone as dictation machine with transmission of voice memory over mobile radio network to target computer

METHOD FOR COOKING BAEK-SOOK(CHICKEN OR DUCK BOILED IN PLAIN WATER) WITH ARALIA ELATA SEEM.

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Vorrichtung zum Bedienen einer technischen Einrichtung, technische Einrichtung, Datenverarbeitungseinrichtung und Rechnerprogramm

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Bildübertragungseinheit und Bildübertragungssystem

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SYSTEM AND METHOD FOR DETERMINING AND CONTROLLING CONTAMINATION