COMBINED INHIBITION OF CASPASE-2 AND CASPASE-6 IN NEUROPROTECTION AND AXON REGENERATION
申请公布号:WO2015136255(A1)
申请号:WO2015GB50683
申请日期:2015.03.09
申请公布日期:2015.09.17
发明人:AHMED, ZUBAIR;LOGAN, ANN;BERRY, MARTIN
分类号:C12N15/113;A61K31/7088;A61K38/48;A61P25/00
主分类号:C12N15/113
摘要:<p>The invention relates to the use of agents for the inhibition of caspase-2 and caspase-6 in the protection of central and peripheral neurons. In particular, the invention comprises an inhibitor of caspase-2 for use in the treatment of a disease, a disorder or an injury of the nervous system by combined, sequential or separate administration with an inhibitor of caspase-6. Further provided is a composition comprising an inhibitor of caspase-2 and an inhibitor of caspase-6.</p>