MERCURY METHYLATION GENES IN BACTERIA AND ARCHAEA,申请号US201314132906-传众专利搜索

MERCURY METHYLATION GENES IN BACTERIA AND ARCHAEA

申请公布号：US2014179553(A1)

申请号：US201314132906

申请日期：2013.12.18

申请公布日期：2014.06.26

申请人：

UT-Battelle, LLC

发明人：Parks Jerry M.;Johs Alexander

分类号：C12Q1/68

主分类号：C12Q1/68

地址：Oak Ridge TN US

摘要：Two genes required for this mercury methylation have been identified in bacteria and archaea. These genes are the hgcA gene and hgcB, a corrinoid protein that facilitates methyl group transfer to Hg, and a corrinoid protein-associated ferredoxin with two [4Fe-4S] binding motifs involved in generating cob(I)almin, respectively. The invention provides nucleic acid probes and primers for detecting methylmercury and or for assessing mercury methylation potential in environmental, clinical and other samples. The invention also provides antibodies against these proteins, antibodies against these proteins, methods of using the antibodies and methods of biocatalysis.