Lutzomyia longipalpis polypeptides and methods of use,申请号US20090350179-传众专利搜索

Lutzomyia longipalpis polypeptides and methods of use

申请公布号：US8628780(B2)

申请号：US20090350179

申请日期：2009.01.07

申请公布日期：2014.01.14

申请人：

VALENZUELA JESUS G.;RIBEIRO JOSE M. C.;BARRAL ALDINA;NETTO MANOEL;BRODSKYN CLAUDIA;GOMES REGIS;THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES;FUNDACAO OSWALDO CRUZ (FIOCRUZ)

发明人：VALENZUELA JESUS G.;RIBEIRO JOSE M. C.;BARRAL ALDINA;NETTO MANOEL;BRODSKYN CLAUDIA;GOMES REGIS

分类号：A61K39/00;A61K38/00;C07K14/435

主分类号：A61K39/00

摘要：Substantially purified salivary Lu. longipalpis polypeptides, and polynucleotides encoding these polypeptides are disclosed. Vectors and host cells including the Lu. longipalpis polynucleotides are also disclosed. In one embodiment, a method is disclosed for inducing an immune response to sand fly saliva. In other embodiments, methods for treating, diagnosing, or preventing Leishmaniasis are disclosed.