Cyclopamine lactam analogs and methods of use thereof

申请公布号：US8431566(B2)

申请号：US201113250080

申请日期：2011.09.30

申请公布日期：2013.04.30

申请人：

CASTRO ALFREDO;GROGAN MICHAEL J.;LESCARBEAU ANDRE;TREMBLAY MARTIN;INFINITY DISCOVERY, INC.

发明人：CASTRO ALFREDO;GROGAN MICHAEL J.;LESCARBEAU ANDRE;TREMBLAY MARTIN

分类号：A61K31/55;C07D491/20

主分类号：A61K31/55

摘要：The present invention relates to steroidal alkaloids useful in the treatment of hedgehog pathway related disorders, particularly cancer.

BIODEGRADABLE PARTICLES

SYSTEM AND METHOD FOR INCREMENTAL BROADCAST OF GPS NAVIGATION DATA IN A CELLULAR NETWORK

Thermoplastic connecting piece for pipelines of a ground probe system

DETERMINING A FLUID FRACTION IN AN EARTH FORMATION

Contact lens transfer and material removal system

Feedstock based on vegetable materials

Process for converting caprolactam to nylon 6

Procedure for the level-independent measurement of the surface-tension of liquid substances

AIR-CONDITIONING SYSTEM

SURGICAL SYSTEM

AGENT FOR IMPROVING TISSUE PENETRATION

APPARATUS AND METHOD VISUALIZING ULTRASONIC IMAGES

Method of sensing a chemical and sensor therefor

METHOD AND APPARATUS FOR MAINTAINING CONSISTENCY OF A SHARED SPACE ACROSS MULTIPLE ENDPOINTS IN A PEER-TO-PEER COLLABORATIVE COMPUTER SYSTEM

ANTISENSE MODULATION OF PTP1B EXPRESSION

BLIND APPARATUS CAPABLE OF EXECUTING ASSEMBLY AND REPAIR QUICKLY, AND LIFTING UP AND DOWN SLAT EASILY

METHOD AND ARRANGEMENT FOR REGULATING THE LIGHT POWER OF A SCANNING BEAM IN AN APPARATUS FOR READING FROM OR FOR WRITING TO OPTICAL RECORDING MEDIA

Temperature sensing device and applications thereof

CARBON MATERIAL, PRODUCTION METHOD AND USE THEREOF

Light absorptive antireflector