DRUG-LOADED POLYSACCHARIDE-COATED GOLDMAG PARTICLES (DPGPs) AND ITS SYNTHESIS METHOD,申请号US200813142820-传众专利搜索

DRUG-LOADED POLYSACCHARIDE-COATED GOLDMAG PARTICLES (DPGPs) AND ITS SYNTHESIS METHOD

申请公布号：US2012121717(A1)

申请号：US200813142820

申请日期：2008.12.30

申请公布日期：2012.05.17

申请人：

CHAO XU;CUI YALI;PENG MINGLI;CHEN CHAO;XIN XIAOFANG;LI KE;HUI WENLI;XI'AN GOLDMAG NANOBIOTECH CO. LTD

发明人：CHAO XU;CUI YALI;PENG MINGLI;CHEN CHAO;XIN XIAOFANG;LI KE;HUI WENLI

分类号：A61K9/14;A61K31/704;A61P31/00;A61P35/00;B05D3/00

主分类号：A61K9/14

摘要：The invention relates to Polysaccharide-coated GoldMag particles (DPGPs) and the method of its synthesis, which characterized GoldMag particles as a core and natural or synthetic biodegradable polysaccharide such as dextran, cyclodextrin and derivatives as shell. DPGPs are synthesized by mixing Polysaccharide-coated GoldMag particles (DPGPs) with drug through physical bond. The preparation of the drug-loaded composite particles include: preparing the polysaccharide-coated GoldMag particles and then loading the drug on the polysaccharide-coated GoldMag particles. The drug-loading process is carried out through directly mixing the polysaccharide-coated GoldMag particles with the drug solution by the shaker. That means the polysaccharide-coated GoldMag particles load the drug through affinity adsorption.