2-Aza-bicyclo[2.2.1]heptane derivatives

申请公布号：NZ588080(A)

申请号：NZ20090588080

申请日期：2009.02.19

申请公布日期：2012.04.27

申请人：

ACTELION PHARMACEUTICALS LTD.

发明人：AISSAOUI, HAMED;BOSS, CHRISTOPH;KOBERSTEIN, RALF;SIFFERLEN, THIERRY;TRACHSEL, DANIEL

分类号：A61K31/427;A61K31/4709;A61P25/00;C07D403/12;C07D405/12;C07D417/06;C07D417/14;C07D471/04;C07D493/04;C07D495/04;C07D513/04

主分类号：A61K31/427

摘要：Disclosed is a 2-aza-bicyclo[2.2.1]heptane derivative of formula (I), or a salt thereof, where n is 0 or 1, A and B are each optionally substituted aryl or heterocycle, and the other substituents are as defined in the specification. Also disclosed is the use of the compound for treating selected all types of sleep disorders, stress related syndromes, psychoactive substance use and abuse, cognitive dysfunctions in the healthy population and in psychiatric and neurologic disorders, and eating or drinking disorders.

DIRECT-INJECTION SPARK-IGNITION INTERNAL COMBUSTION ENGINE

AIR FUEL RATIO CONTROL DEVICE FOR INTERNAL COMBUSTION ENGINE

FUEL FRACTIONAL DISTILLATION DEVICE OF INTERNAL COMBUSTION ENGINE

ELECTROMAGNETIC PUMP

GEAR DEVICE AND KICK STARTER OF ENGINE

AERIAL AIR-COOLED DEVICE OF VERTICAL ELECTRIC PUMP

INTAKE SYSTEM PART MOUNTING STRUCTURE

THERMOSTAT AND VEHICLE COOLING CIRCUIT HAVING THERMOSTAT

CONTROL DEVICE OF INTERNAL COMBUSTION ENGINE

METHOD AND MACHINE ARRANGEMENT FOR CHANGING TRACK INTO STRONG TRAVEL PASSAGE

CONCRETE FLOOR CONSTRUCTION OF DETACHED BASE-ISOLATED HOUSE

TOP TYPE BASE-ISOLATING APPARATUS

WATER STOP DEVICE IN CASE OF EMERGENCY

MOVING TYPE PARTITION DEVICE

NEGATIVE PRESSURE DESTRUCTOR FOR WATER-SERVICE INSTALLATION

GRAVESTONE AND INCENSE BURNER

DESIGN METHOD OF CUSHIONING MATERIAL IN CURVE JACKING OF JACKING PIPE

REPAIR METHOD FOR PAINTED SURFACE OF EXTERIOR WALL, AND EXTERIOR WALL PAINTING STRUCTURE

FLAT TYPE DOOR LOCK HANDLE DEVICE

BUILDING CONSTRUCTION PANEL COMBINATION BODY, ITS MANUFACTURING METHOD, AND BUILDING CONSTRUCTION METHOD USING IT