METHOD TO BLOCK THE INFECTION BY FLAVIVIRUSES, MOLECULES AND USES,申请号US20070298808-传众专利搜索

METHOD TO BLOCK THE INFECTION BY FLAVIVIRUSES, MOLECULES AND USES

申请公布号：US2011212105(A1)

申请号：US20070298808

申请日期：2007.04.26

申请公布日期：2011.09.01

申请人：

HUERTA GALINDO VIVIAN;CHINEA SANTIAGO GLAY;FLEITAS SALAZAR NORALVIS;MARTIN DUNN ALEJANDRO MIGUEL;SARRIA NUNEZ MONICA;GUIROLA CRUZ OSMANY;TOLEDO MAYORA PATRICIA GABRIELA;SANCHEZ PUENTE ANIEL;BESADA PEREZ VLADIMIR ARMANDO;REYES ACOSTA OSVALDO;GARAY PEREZ HILDA ELISA;CABRALES RICO ANIA;MUSACCHIO LASA ALEXIS;PADRON PALOMARES GABRIEL RAMON;GONZALEZ LOPEZ LUIS JAVIER

发明人：HUERTA GALINDO VIVIAN;CHINEA SANTIAGO GLAY;FLEITAS SALAZAR NORALVIS;MARTIN DUNN ALEJANDRO MIGUEL;SARRIA NUNEZ MONICA;GUIROLA CRUZ OSMANY;TOLEDO MAYORA PATRICIA GABRIELA;SANCHEZ PUENTE ANIEL;BESADA PEREZ VLADIMIR ARMANDO;REYES ACOSTA OSVALDO;GARAY PEREZ HILDA ELISA;CABRALES RICO ANIA;MUSACCHIO LASA ALEXIS;PADRON PALOMARES GABRIEL RAMON;GONZALEZ LOPEZ LUIS JAVIER

分类号：A61K39/42;A61K38/16;C07K7/08

主分类号：A61K39/42

摘要：The present invention is related to a method for blocking the infection of cells by dengue virus, based on interfering the direct interaction of the viral envelope protein with a cellular receptor or its indirect interaction with said cellular receptor through a carrier protein, as well as related uses; wherein said cellular receptor is the alpha-2 macroglobulin receptor, also known as the low density receptor-related protein or as CD91, and said carrier protein is human alpha-2 macroglobulin.