MICROFLUIDIC PLATFORM FOR DISCRETE CELL ASSAY
申请公布号:WO2011056643(A2)
申请号:WO2010US54257
申请日期:2010.10.27
申请公布日期:2011.05.12
发明人:YOON, EUISIK;YOUNG-JI, KIM
分类号:G01N35/00;C12M3/00;C12Q1/04;G01N1/28;G01N33/48
主分类号:G01N35/00
摘要:A microfluidic chamber for use in individual cell assays. The microfluidic chamber includes a cell microchamber having an interior region and front and rear valves, each of which are separately controllable so that they can be selectively opened and closed to thereby permit the transference of an individual cell into and out of the interior region. Cell secretion and contact interaction studies can be carried out using the microchambers, with the valves permitting either complete isolation or perfusion media flow through the microchambers. An internal perfusion wall can be included to partition the microchamber for non-contact perfusion studies of secretion interactions between cells.
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