Cyclopropyl derivatives as NK3 receptor antagonists,申请号NZ20040544935-传众专利搜索

Cyclopropyl derivatives as NK3 receptor antagonists

申请公布号：NZ544935(A)

申请号：NZ20040544935

申请日期：2004.08.13

申请公布日期：2009.08.28

申请人：

H. LUNDBECK A/S

发明人：KEHLER, JAN;HANSEN, TORE;POULSEN, ANDERS;BJORNHOLM, BERITH;RUHLAND, THOMAS;NORGAARD, MORTEN BANG;NIELSEN, SOREN MOLLER

分类号：C07D211/58;A61K31/435;A61K31/495;A61P25/00;C07D211/14;C07D211/32;C07D211/52;C07D211/64;C07D471/10;C07D471/20

主分类号：C07D211/58

摘要：Disclosed is a compound of formula (I), or a pharmaceutically acceptable salt thereof, wherein n is 0, 1, or 2, Q is selected from (i), (ii), or (iii), and wherein the other substituents are as defined in the specification. Also disclosed is the use of the compound to treat psychotic disorders, schizophrenia, depression, anxiety, Parkinson's disease, pain, convulsions, cough, asthma, airway hyperresponsiveness, microvascular hypersensitivity, bronchoconstriction, gut inflammation, inflammatory bowel disease, hypertension, imbalances in water and electrolyte homeostasis, ischemia, oedema, plasma extravasation, obesity, and schizophrenia.