CYCLOALIPHATIC PHARMACEUTICAL COMPOUNDS
申请公布号:CA1246604(A)
申请号:CA19840444901
申请日期:1984.01.09
申请公布日期:1988.12.13
发明人:KASHA, WALTER J.
分类号:C07C35/00;C07C49/487;C07C49/517;(IPC1-7):C07C35/00
主分类号:C07C35/00
摘要:<p>Novel pharmaceutical compounds, useful in anti-? genic compositions, have the formulae: (I) (II) In these formulae: B and B' are both H or together form a single bond; M1 and M2 are H, Cl, Br or I Q is CO, CH-OR, or CR-OH; each X is independently H or A; Y and Y' are independently H, halo. or A; A is -CRR-(CR1R2)nR3 n is an integer of from one to eight; R is H or lower alkyl; each R1 and R2 is independently R, OR, COOH, CHO, or CR1R2 together form the group CO; R3 is H, COOR, OR, CHR-OR or COR; c is an integer from zero to four; and d is three or four; and p is zero or one provided that at least one A group is present and each A group contains at least one of COOR, CHO, CO, OR and COR, and not more than one of COOH, CO or COR, and wherein up to two ethylenic bonds may be present in the ring shown above. Pharmaceutically-acceptable salts of these compounds also are provided.</p>
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