Prenatal diagnosis method on isolated foetal cell of maternal blood,申请号AU20020314224-传众专利搜索

Prenatal diagnosis method on isolated foetal cell of maternal blood

申请公布号：AU2002314224(B2)

申请号：AU20020314224

申请日期：2002.04.30

申请公布日期：2007.08.02

申请人：

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE;ASSISTANCE PUBLIQUE-HOPITAUX DE PARIS;UNIVERSITE RENE DESCARTES PARIS 5

发明人：PATRIZIA PATERLINI-BRECHOT

分类号：G01N33/50;C12N15/09;C12Q1/02;C12Q1/68;G01N33/68

主分类号：G01N33/50

摘要：The invention concerns a novel non-invasive prenatal diagnostic method implemented with a sample of maternal blood. Said method enables prenatal diagnosis on isolated non-apoptotic epithelial foetal cells of maternal blood after they have been enriched by filtration, morphologically or immunologically and genetically analysed. Said method is advantageous in that it is perfectly harmless for the mother and the foetus and provides a highly sensitive and specific diagnosis. It enables early detection of a genetic or chromosomal abnormality of the foetus, of a genetic or infectious (viral, bacterial or parasitic) pathology of the foetus, of accurate genotype, and in particular of the genetic sex of the foetus.