Pyrrolopyrimidine and pyrrolopyridine derivatives substituted with cyclic amino group,申请号EP20060019987-传众专利搜索

Pyrrolopyrimidine and pyrrolopyridine derivatives substituted with cyclic amino group

申请公布号：EP1787992(A1)

申请号：EP20060019987

申请日期：2003.12.24

申请公布日期：2007.05.23

申请人：

TAISHO PHARMACEUTICAL CO., LTD

发明人：NAKAZATO, ATSURO;OKUBO, TAKETOSHI;NOZAWA, DAI;YAMAGUCHI, MIKAKO;TAMITA, TOMOKO;KENNIS, LUDO E. J.;DE BRUYN, MARCEL F.L.;BONGARTZ, JEAN-PIERRE A. M.;VAN DEN KEYBUS, FRANS M.A.;VAN ROOSBROECK, YVES E.M.;LUYCKX, MARCEL G.M.;HENDRICKX, ROBERT J.M.

分类号：C07D487/04;A61K31/436;A61K31/437;A61K31/4375;A61K31/439;A61K31/519;A61K31/661;A61P1/00;A61P1/04;A61P9/10;A61P9/12;A61P17/00;A61P17/14;A61P25/00;A61P25/08;A61P25/14;A61P25/16;A61P25/18;A61P25/22;A61P25/24;A61P25/28;A61P25/36;A61P29/00;A61P37/00;A61P43/00;C07D209/00;C07D221/00;C07D239/00;C07D451/00;C07D471/00;C07D471/04;C07D471/08;C07D487/00;C07D491/00;C07D491/08;C07D519/00;C07F9/59;C07F9/6561

主分类号：C07D487/04

摘要：An object of the present invention is to provide an antagonist against CRF receptors which is effective as a therapeutic or prophylactic agent for diseases in which CRF is considered to be involved, such as depression, anxiety, Alzheimer's disease, Parkinson's disease, Huntington's chorea, eating disorder, hypertension, gastric diseases, drug dependence, epilepsy, cerebral infarction, cerebral ischemia, cerebral edema, cephalic external wound, inflammation, immunity-related diseases, alopecia, irritable bowel syndrome, sleep disorders, epilepsy, dermatitides, schizophrenia, etc. [SOLUTION] A pyrrolopyrimidine or pyrrolopyridine derivative substituted with a cyclic amino group represented by the following formula [I]: has a high affinity for CRF receptors and is effective against diseases in which CRF is considered to be involved.