DEVICE AND METHOD FOR MONITORING LEUKOCYTE MIGRATION,申请号WO2003US33177-传众专利搜索

DEVICE AND METHOD FOR MONITORING LEUKOCYTE MIGRATION

申请公布号：WO2004038368(A2)

申请号：WO2003US33177

申请日期：2003.10.21

申请公布日期：2004.05.06

申请人：

SURFACE LOGIX, INC.;KIRK, GREGORY, L.;KIM, ENOCH;OSTUNI, EMANUELE;SCHUELLER, OLIVIER;SWEETNAM, PAUL

发明人：KIRK, GREGORY, L.;KIM, ENOCH;OSTUNI, EMANUELE;SCHUELLER, OLIVIER;SWEETNAM, PAUL

分类号：A01N1/02;B01L3/00;C12M1/00;C12N5/08;C12Q1/02;G01N;G01N25/10;G01N33/50;G01N33/53;G01N33/543;G01N33/554

主分类号：A01N1/02

摘要：A device for monitoring leukocyte migration is provided. The invention also provides a method of using the device to monitor leukocyte migration in the presence of physiological shear flow and therefore simulate physiological conditions of a blood vessel in vivo. The invention further provides a method of using the device to high-throughput screen a plurality of test agents. The present invention further provides a flexible assay system and numerous assays that can be used to test biological interactions and systems. Laminar flow gradients are employed mimic gradient situations present in vivo.