Compounds

申请公布号：US6337394(B2)

申请号：US19980214143

申请日期：1998.12.29

申请公布日期：2002.01.08

申请人：

ASTRAZENECA AB

发明人：KARLSSON OLLE;LINSCHOTEN MARCEL;NYSTROEM JAN-ERIK

分类号：A61K38/00;A61P7/02;A61P43/00;C07D207/16;C07K5/06;(IPC1-7):A01N61/00;A01N43/04;C07D345/00;C07D223/04;C07D213/00

主分类号：A61K38/00

摘要：There is provided compounds of formula I,wherein R1, R2, R3, Rx, Y, n and B have meanings given in the description which are useful as competitive inhibitors of trypsin-like proteases, such as thrombin, and in particular in the treatment of conditions where inhibition of thrombin is required (e.g. thrombosis) or as anticoagulants.

FECES-CATCHING DEVICE FOR PET (DOG/CAT OR THE LIKE)

SACCHARIDE PURIFICATION METHOD USING YEAST

FIELD BLOWING METHOD PREVENTING GEOTHERMAL HEAT OF FIELD AND/OR HEAT RADIATION OF TEA FRUIT TREE HEAT WITH AIR CURTAIN

THRESHER

METHOD FOR RAISING SHELLFISHES

OFDM TRANSMISSION WITH LOW LATENCY THROUGH USE OF A PILOT SYMBOL AT THE END OF THE TRANSMIT SUBFRAME

FLOWMETER FOR DETERMINING A FLOW DIRECTION

HETEROBICYCLIC CARBOXAMIDES AS INHIBITORS FOR KINASES

COMBINED PUMP HOUSING FOR SEVERAL RATED QUANTITIES

PRINTING PRESS AND METHOD FOR SETTING THE POSITION OF ITS PRINTING UNIT

DISPLAY DEVICE FOR THE ANALOGUE DISPLAY OF VARIABLES, PARAMETERS ETC.

MULTIPLE-CONTAINER BUNDLE

TOOTHBRUSH AND TOOTHBRUSH HEAD FOR SAID TOOTHBRUSH

COATING OF CARBOHYDRATE MATERIALS

HYDRAULIC CONTROL FOR A DUAL CLUTCH TRANSMISSION

BARBECUE

METHOD AND DEVICE FOR PRODUCING A CONTAINER

Schaltvorrichtung

SYSTEM AND METHOD FOR COLLECTING AND UPDATING GEOGRAPHICAL DATA

PROCESS FOR PRODUCTION OF CYCLOPROPYLAMIDE COMPOUND