POSTUPAK ZA UKLANJANJE OTPADNOG POx, ALENDRONATA I NJEGOVIH NUSPROIZVODA

申请公布号：YU36295(A)

申请号：YU19950000362

申请日期：1995.05.30

申请公布日期：1998.05.15

申请人：

MERCK & CO. INC.

发明人：VENKATARAMANI, E.;FORMAN, A.L.;MAGLIETTE, R.J.JR.;MCKINNEY, D.

分类号：C02F1/52;C02F101/30;C02F103/36;C07F9/38

主分类号：C02F1/52

摘要：Disclosed is a process for removing by-product phosphorus-containing (POx) materials, alendronate and alendronate byproducts from crude mother liquors in an omega amino-1-hydroxy-C2-C6 alkylidene-1,1-bisphosphonic acid synthesis process, e.g. alendronate sodium. Calcium chloride is added first to the crude mother liquors, then calcium oxide to precipitate the POx materials, then neutralized to about pH 7 to complete precipitation. Substantially all of the alendronate sodium active ingredient is removed from the precipitate. Following filtration, the POx filtercake can then be disposed of by incineration, landfilling or reclamation of usable phosphorus as fertilizer. The remaining filtrate can then be further treated in an environmentally acceptable manner by wastewater treatment or recycling to the process.

MAGNETO-OPTICAL INFORMATION RECORDER

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MATERIAL EM CAMADAS OU PECA EM CAMADAS E PROCESSO PARA A SUA PRODUCAO

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FELDHAECKSLER

VERFAHREN ZUR MODIFIZIERUNG DER OBERFLAECHE VON GLASSUBSTRATEN

MIKROCOMPUTERSYSTEM MIT MIKROPROZESSORRUECKSETZSCHALTUNG

VERWENDUNG VON AUSSCHEIDUNGSHAERTENDEN FERRITISCH-PERLITISCHEN (AFP-)STAEHLEN ALS WERKSTOFF FUER GASWECHSELVENTILE VON VERBRENNUNGSMOTOREN

LESEVERSTAERKERTREIBER ZUR VERWENDUNG IN EINEM SPEICHER

DOUBLER AND TRIPLER FOR A VOLTAGE SOURCE

ABZIEHLAUFSCHIENE.

COMPOSITIONS TO REDUCE DELETERIOUS EFFECTS OF SPOILAGE¹ENZYMES

MESSWERTUMFORMER UND VERFAHREN ZUR KORREKTUR SEINES AUSGANGSSIGNALS.

NUKLEARBINDUNGSTEST FUER STEROIDREZEPTORSFUNKTION IN KREBSARTIGEN ZELLEN.

VERFAHREN ZUR HERSTELLUNG VON VINYLACETAT

LICHTEMPFINDLICHES FARBPHOTOGRAPHISCHES SILBERHALOGENIDMATERIAL.

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