THERAPEUTIC METHOD FOR TREATMENT OF ALZHEIMER'S DISEASE,申请号US1997007661-传众专利搜索

THERAPEUTIC METHOD FOR TREATMENT OF ALZHEIMER'S DISEASE

申请公布号：WO1997040879(A1)

申请号：US1997007661

申请日期：1997.04.18

申请公布日期：1997.11.06

摘要：<p>A method and apparatus for treating Alzheimer's disease is disclosed. The method comprises delivering indomethacin or nonsteroidal anti-inflammatory agents having cyclooxygenase inhibitor action directly to the hippocampus or the lateral ventricle throuh an implanted catheter. The catheter has a flexible distal end that is implanted directly in the hippocampus or lateral ventricle as the preferred embodiment. The distal end has either a porous tip or a closed end. Where the distal end is closed, or a plurality of elution holes are present, indomethacin is delivered to the hippocampus or lateral ventricle through either the porous tip or the elution holes. The catheter is part of a system for delivering indomethacin or nonsteroidal anti-inflammatory agents having cyclooxygenase inhibitor action to the hippocampus or lateral ventricle that includes a pump coupled to the catheter for delivering the indomethacin or nonsteroidal anti-inflammatory agents having cyclooxygenase inhibitor action through the catheter to the hippocampus or lateral ventricle.</p>