METHOD OF MAKING 2,7-DIMETHYL-2,4,6-OCTATRIENEDIAL, A KEY INTERMEDIATE IN THE COMMERCIAL SYNTHESES OF VARIOUS CAROTENOIDS,申请号WO1995US13372-传众专利搜索

METHOD OF MAKING 2,7-DIMETHYL-2,4,6-OCTATRIENEDIAL, A KEY INTERMEDIATE IN THE COMMERCIAL SYNTHESES OF VARIOUS CAROTENOIDS

申请公布号：WO9616013(A1)

申请号：WO1995US13372

申请日期：1995.10.11

申请公布日期：1996.05.30

申请人：

LOYOLA UNIVERSITY OF CHICAGO

发明人：BABLER, JAMES, H.

分类号：C07C45/00;C07C45/64;C07C45/70;C07C45/71

主分类号：C07C45/00

摘要：A procedure for forming methylmalonaldehyde from propionaldehyde, an alkyl formate and a sodium alkoxide, utilizing a crossed-Claisen condensation is disclosed. The procedure avoids the formation of aldol condensation products. Also disclosed are processes for preparing 3-alkoxy-2-methylpropenals such as 2-methyl-3-(2-methyl-2-propenoxy)propenal from methylmalonaldehyde. The latter products are useful in the synthesis of carotenoids.