DIPYRIDAMOLE SUSTAINED RELEASE FORMULATINS AND PROCESSES FOR THEIR PREPARATION,申请号KE19840003402-传众专利搜索

DIPYRIDAMOLE SUSTAINED RELEASE FORMULATINS AND PROCESSES FOR THEIR PREPARATION

申请公布号：KE3402(A)

申请号：KE19840003402

申请日期：1984.04.12

申请公布日期：1984.06.08

申请人：

DR KARL THOMAE GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG

发明人：PETER GRUBER;ROLF BRICKL;HERBERT STRICKER;GERHARD BOZLER

分类号：A61K9/16;A61K9/22;A61K9/24;A61K9/48;A61K9/50;A61K9/52;A61K9/54;A61K9/56;A61K31/505;A61P9/08;A61P9/10

主分类号：A61K9/16

摘要：This invention relates to a composition for the sustained release of dipyridamole which comprises (i) spheroid particles comprised of dipyridamole or crystallized salts thereof and pharmacologically acceptable acid or acid substance, and (ii) a coating surrounding said spheroid particles, said coating being comprised of from about 50 to 100 percent by weight of acid-insoluble lacquers soluble in intestinal juices and from about 0 to 50 percent by weight of lacquers insoluble in gastric and intestinal juices and said coating being present in an amount of from about 3 to 30 percent by weight, based on the weight of the spheroid particles, and to the preparation of such a composition.