UN PROCEDIMIENTO PARA LA PREPARACION DE COMPUESTOS HETEROCI-CLICOS SUSTITUIDOS EN EL GRUPO HIDROXI

申请公布号：ES484117(A1)

申请号：ES19170004841

申请日期：1979.09.12

申请公布日期：1980.09.01

申请人：

EISONS LIMITED

分类号：A61K31/35;C07D311/92;(IPC1-7):07D311/92;61K31/35

主分类号：A61K31/35

摘要：<p>Un procedimiento para la preparación de derivados del ácido 6,7,8,9-tetrahidro-4-oxo-10-propil-4H-nafto-(2,3-b)-piran-2-carboxílico. La ciclisación del procedimiento puede llevarse a cabo calentando, o en condiciones básicas o neutras. Sin embargo se prefiere llevar a cabo la ciclisación en presencia de un ácido, por ejemplo ácido clorhídrico, y en un disolvente que es inerte en las condiciones de reacción, por ejemplo etanol. La reacción puede llevarse a cabo de aproximadamente 20º a 150ºC.</p>

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