PROCESS FOR PRODUCING L-PROLINE

申请公布号：US3650899(A)

申请号：USD3650899

申请日期：1968.06.14

申请公布日期：1972.03.21

申请人：

KYOWA HAKKO KOGYO CO. LTD.

发明人：YUICHI NOGUCHI;TORU NAKANISHI;YASUYUKI TAKETUGU

分类号：C12P13/24;(IPC1-7):C12D1/02

主分类号：C12P13/24

摘要：A process for producing L-proline by fermentation which comprises culturing a micro-organism capable of producing L-proline under aerobic conditions in an aqueous nutrient medium containing biotin, in an amount at least sufficient for the growth of the bacterial cells, and at least 0.5 mole per liter each of ammonium ion and chloride ion. A convenient supply of the said ions is ammonium chloride. Preferred micro-organism are Micrococcus glutamicus ATCC 21157, 21158 and 21159.

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