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BIODEGRADABLE SHAPE MEMORY POLYMERS

申请公布号:WO9942147(A1)

申请号:WO1999US03977

申请日期:1999.02.23

申请公布日期:1999.08.26

申请人:
MASSACHUSETTS INSTITUTE OF TECHNOLOGY

发明人:LANGER, ROBERT, S.;LENDLEIN, ANDREAS;SCHMIDT, ANNETTE;GRABLOWITZ, HANS

分类号:A61C7/00;A61B17/58;A61F5/01;A61K47/30;A61L27/00;A61L27/14;A61L27/18;A61L27/50;A61L27/58;A61L29/00;A61L29/04;A61L29/14;A61L31/00;A61L31/04;A61L31/14;C08G18/48;C08L101/00;C08L101/16;(IPC1-7):A61L27/00

主分类号:A61C7/00

摘要:Biodegradable shape memory polymer compositions, articles of manufacture thereof, and methods of preparation and use thereof are described. In one embodiment the compositions include at least one hard segment and at least one soft segment. The Ttrans of the hard segment is preferably between -30 and 270 DEG C. At least one of the hard or soft segments can contain a cross-linkable group, and the segments can be linked by formation of an interpenetrating network or a semi-interpenetrating network, or by physical interactions of the segments. Objects can be formed into a given shape at a temperature above the Ttrans of the hard segment, and cooled to a temperature below the Ttrans of the soft segment. If the object is subsequently formed into a second shape, the object can return to its original shape by heating the object above the Ttrans of the soft segment and below the Ttrans of the hard segment.

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