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Method of Inhibiting the Glycation of Nutrient and Endogenous Proteins and Peroxidation of Nutrient and Endogenous Lipids

申请公布号:US2016324844(A1)

申请号:US201514708276

申请日期:2015.05.10

申请公布日期:2016.11.10

申请人:
Ambatipudi Mythri

发明人:Ambatipudi Mythri

分类号:A61K31/455;A61K31/375;A61K31/355;A61K31/352;A61K31/353;A61K31/417;A61K31/05

主分类号:A61K31/455

地址:San Jose CA US

摘要:Methods for reducing the glycation of nutrient and endogenous proteins and methods for reducing the peroxidation of nutrient and endogenous lipids are provided herein. Several inhibitors and conditions of inhibiting glycation of nutrient and endogenous proteins and peroxidation of nutrient and endogenous lipids are also provided herein. Also provided are the methods for inhibiting and treating the conditions associated with the formation of glycated proteins, such as Alzheimer's disease, neuropathy, retinopathy and nephropathy and the methods for inhibiting and treating the conditions associated with the formation of peroxidized lipids, such as cancer and atherosclerosis.

主权项:1. A method of inhibiting the glycation of a nutrient protein comprising: a. Providing said nutrient protein is combined with a reducing sugar and a natural or synthetic inhibiting agent and thermally processed at a temperature of less than 60 degree Celsius in a neutral or mildly acidic environment. b. Wherein said reducing sugar is selected from a group comprised of ribose, fructose, glucose, lactose or maltose or a plurality or a combination thereof c. Wherein said inhibiting agent is selected from a group comprised of flavonoid, a chelating agent and an antioxidant or a plurality or a combination thereof d. Wherein said flavonoid is selected from a group comprised of an anthocyanin, a phenol or a catechin or a plurality or a combination thereof e. Wherein said antioxidant is selected from a group comprised of tocopherol, niacinamide and ascorbic acid or a plurality or a combination thereof f. Wherein said chelating agent is carnosineWhereby the glycation of said nutrient protein will be inhibited.

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