Tert aminomethyl pentenyl dioxolanes - vasodilators hypotensives spasmolytics diuretics and analgesics,申请号FR19710044689-传众专利搜索

Tert aminomethyl pentenyl dioxolanes - vasodilators hypotensives spasmolytics diuretics and analgesics

申请公布号：FR2163322(A1)

申请号：FR19710044689

申请日期：1971.12.13

申请公布日期：1973.07.27

申请人：

DELALANDE

分类号：C07D317/28;(IPC1-7):61K27/00;07D13/00

主分类号：C07D317/28

摘要：<p>Title cpds. are of formula (I) where R1 and R2 = =4C alkyl, or together with the N atom form a pyrrolidino, piperidino hexamethyleneimino or morpholino ring. They are prepd. by reaction of the corresp. 4-bromomethyl dioxolane (II) with the secondary amine R1-NH-R2. In an example, 0.15 mole (II) in dry toluene was treated with 0.75 mole pyrrolidine and refluxed for 8-14 hrs. to give a 67% yield of (I) R1NR2=pyrrolidino b. pt. 140-141 degrees C/5 mm Hr.</p>