DECARBOXYLATIVE CROSS-COUPLING AND APPLICATIONS THEREOF,申请号EP20150773756-传众专利搜索

DECARBOXYLATIVE CROSS-COUPLING AND APPLICATIONS THEREOF

申请公布号：EP3126545(A2)

申请号：EP20150773756

申请日期：2015.03.27

申请公布日期：2017.02.08

申请人：

The Trustees of Princeton University

发明人：MACMILLAN, David, W.C.;ZUO, Zhiwei

分类号：C25B3/10

主分类号：C25B3/10

摘要：Methods described herein enable the production of numerous molecular species through decarboxylative cross-coupling via use of photoredox and transition metal catalysts. For example, methods described herein enable the production of numerous molecular species through decarboxylative cross-coupling via use of photoredox and transition metal catalysts. A method described herein, in some embodiments, comprises providing a reaction mixture including a photoredox catalyst, a transition metal catalyst, a coupling partner and a substrate having a carboxyl group. The reaction mixture is irradiated with a radiation source resulting in cross-coupling of the substrate and coupling partner via a mechanism including decarboxylation, wherein the coupling partner is selected from the group consisting of a substituted aromatic compound and a substituted aliphatic compound.