ANTIBODY BASED REAGENTS THAT SPECIFICALLY RECOGNIZE NEURODEGENERATIVE DISEASE RELATED FORMS OF THE PROTEIN TDP-43,申请号US201515114356-传众专利搜索

ANTIBODY BASED REAGENTS THAT SPECIFICALLY RECOGNIZE NEURODEGENERATIVE DISEASE RELATED FORMS OF THE PROTEIN TDP-43

申请公布号：US2017010284(A1)

申请号：US201515114356

申请日期：2015.02.02

申请公布日期：2017.01.12

申请人：

Arizona Board of Regents on Behalf of Arizona State University

发明人：SIERKS Michael;WILLIAMS Stephanie;VENKATARAMAN Lalitha

分类号：G01N33/68;C07K16/18

主分类号：G01N33/68

地址：Scottsdale AZ US

摘要：The invention relates to antibodies, antibody fragments and binding agents that specifically recognize TDP-43 associated with frontotemporal dementia (FTD), but not TDP-43 associated with amyotrophic lateral sclerosis (ALS) or TDP-43 associated with healthy human brain tissue, and antibodies, antibody fragments and binding agents that specifically recognize TDP-43 associated with ALS, but not TDP-43 associated FTD or TDP-43 associated with healthy human brain tissue.

主权项：1. An antibody or antibody fragment that specifically recognizes TDP-43 associated with frontotemporal dementia (FTD), but not TDP-43 associated with amyotrophic lateral sclerosis (ALS) or TDP-43 associated with healthy human brain tissue.