ALTERNATIVE PATHWAY SPECIFIC ANTIBODIES FOR TREATING HEMOLYTIC DISEASES
申请公布号:EP2904014(A4)
申请号:EP20130843349
申请日期:2013.10.04
申请公布日期:2016.09.28
发明人:BANSAL, REKHA
分类号:C07K16/40;A61K39/395;A61P7/04;A61P35/00;C07K16/18
主分类号:C07K16/40
摘要:A method of treating a hemolytic disorder in a subject in need thereof includes administering to the subject a therapeutically effective amount of an antibody that binds to a component of alternative pathway C3 convertase and selectively inhibits C3a, C5a, C3b, C5b, and C5b-9 produced exclusively by the alternative pathway, without inhibiting any of the classical pathway's ability to produce C3a, C5a, C3b, C5b, and C5b-9.