IRON-BASED MONTMORILLONITE MEDICAMENT FOR TREATING HYPERPHOSPHATEMIA AND IRON-DEFICIENCY ANEMIA, AND PREPARATION METHOD THEREFOR
申请公布号:EP2997970(A1)
申请号:EP20130884765
申请日期:2013.08.15
申请公布日期:2016.03.23
发明人:YANG, YIJUAN;LIU, GANG;QIAO,MIN
分类号:A61K33/26;A61K9/14;A61K31/192;A61K33/12;A61K35/02;A61P7/08
主分类号:A61K33/26
摘要:The present invention relates to an iron-based montmorillonite medicine for treating hyperphosphatemia and iron deficiency anaemia, and the preparation method thereof. The medicine comprises effective ingredient iron-based montmorillonite (Fe-montmorillonite) which is obtained by soaking or eluting the medicinal montmorillonite by water soluble iron salt solution. The effective ingredient is added by pharmaceutic adjuvant or not to make medicanent which is given via gastrointestinal tract. The effective ingredient binds the phosphate in the patients' digestive tract to form insoluble matter which can be excreted from the body via the digestive tract, therefore the phosphate in the patients with chronic renal failure is reduced and the goal of treating hyperphosphatemia is achieved. Meanwhile, the iron ion, which is dissociated from iron-based montmorillonite (Fe-montmorillonite) and is unbound to the phosphate, is absorbed by the human body and supplies the iron ions in the body, therefore the goal of treating iron deficiency anaemia of the patients with chronic renal failure is achieved. The medicine can also be used as preventive against hyperphosphatemia and iron deficiency anaemia of the patients with chronic renal failure.