NOVEL CYCLOSPORIN DERIVATIVES FOR THE TREATMENT AND PREVENTION OF A VIRAL INFECTION,申请号US201514928110-传众专利搜索

NOVEL CYCLOSPORIN DERIVATIVES FOR THE TREATMENT AND PREVENTION OF A VIRAL INFECTION

申请公布号：US2016052972(A1)

申请号：US201514928110

申请日期：2015.10.30

申请公布日期：2016.02.25

申请人：

S&T Global Inc.

发明人：SU Zhuang;HUANG Zhennian;LONG Zhengyu;YANG Suizhou

分类号：C07K7/64

主分类号：C07K7/64

地址：Woburn MA US

摘要：The present invention relates to a compound of the formula (I):;;or pharmaceutically acceptable salt thereof, wherein the symbols are as defined in the specification; a pharmaceutical composition comprising the same, a method for treating or preventing a viral infection using the same.

主权项：1. A compound of formula (I):or pharmaceutically acceptable salt thereof, wherein the symbols have the following meanings and are, for each occurrence, independently selected: R1 is n-butyl or (E)-but-2-enyl; R2 is ethyl, 1-hydroxyethyl, isobutyl or n-butyl; W is O or S; R3 is alkyl or substituted alkyl, alkenyl or substituted alkenyl, alkynyl or substituted alkynyl, cycloalkyl or substituted cycloalkyl, or cycloalkenyl or substituted cycloalkenyl; and R5 is H or methyl.