FORMULATIONS WHICH STABILIZE AND INHIBIT PRECIPITATION OF IMMUNOGENIC COMPOSITIONS,申请号EP20070760907-传众专利搜索

FORMULATIONS WHICH STABILIZE AND INHIBIT PRECIPITATION OF IMMUNOGENIC COMPOSITIONS

申请公布号：EP2010219(A2)

申请号：EP20070760907

申请日期：2007.04.19

申请公布日期：2009.01.07

申请人：

WYETH

发明人：KHANDKE, LAKSHMI;CHEN, YING;HAN, HANYOUNG;SEID, ROBERT, CHANCEY, JR.;JIN, ZHAOWEI;LOOK, JEE, LOON;MALONE, RONALD;YANG, XUDONG

分类号：A61K39/09;A61K39/00;A61K39/095;A61K47/26;A61K47/48

主分类号：A61K39/09

摘要：<p>The present invention addresses an ongoing need in the art to improve the stability of immunogenic compositions such as polysaccharide-protein conjugates and protein immunogens. The invention broadly relates to novel formulations which stabilize and inhibit precipitation of immunogenic compositions. More particularly, the invention described hereinafter, addresses a need in the art for formulations which stabilize and inhibit particulate formation (e.g., aggregation, precipitation) of immunogenic compositions which are processed, developed, formulated, manufactured and/or stored in container means such as fermentors, bioreactors, vials, flasks, bags, syringes, rubber stoppers, tubing and the like.</p>