POLYPEPTIDES AND METHODS OF USE
申请公布号:CA2690734(A1)
申请号:CA20082690734
申请日期:2008.06.16
申请公布日期:2008.12.24
发明人:CLARK, RICHARD A.
分类号:A61K38/04;A61K38/00;C07K5/00;C07K7/06
主分类号:A61K38/04
摘要:Described herein are fragments of fibronectin and vitronectin and variants thereof that have certain activities, including growth factor-binding activity. Also described are fragments of growth factors that bind to fibronectin and inhibit binding of full-length growth factors to fibronectin. Compositions containing such fragments are useful in cosmetic treatments (e.g., the treatment of wrinkles or UV photodamage of skin), and the treatment of wounds and cancer.