Composition
申请公布号:GB2518826(A)
申请号:GB20130017196
申请日期:2013.09.27
申请公布日期:2015.04.08
发明人:THANASIS ATHANASIOU
分类号:A61K35/644;A61K9/00;A61K31/045;A61K47/02;A61K47/20;A61P31/10
主分类号:A61K35/644
摘要:<p>A pharmaceutical composition comprises: an active pharmaceutical ingredient, preferably an antimycotic agent, suitable for treating a disease or condition of the skin; dimethyl sulfoxide (DMSO); and a humectant. Preferably the antifungal agent is capable of inactivating or killing fungi of a genus selected from the group consisting of Trichophyton, Epidermophyton, Microsporum, Aspergillus, Scopulariopsis and Candida. Preferably the antifungal agent is or comprises propolis. The humectant is preferably an ionic salt, in particular magnesium sulphate. Preferably the composition comprises 5 to 10% by weight antifungal agent; 5 to 15% by weight dimethyl sulfoxide; and 10 to 20% by weight magnesium sulfate. The composition is useful in treating a fungal infection, such as onychomycosis (fungal nail infection) selected from distal subungal onychomycosis, white superficial anychomycosis, proximal onychomycosis or candidal anychomycosis; or tinea pedis (atheletes foot).</p>
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