COMPOSITION OF TUMOR-ASSOCIATED PEPTIDES AND RELATED ANTI-CANCER VACCINE FOR THE TREATMENT OF GLIOBLASTOMA (GBM) AND OTHER CANCERS

申请公布号：PT2172211(E)

申请号：PT20080017305T

申请日期：2008.10.01

申请公布日期：2015.03.09

申请人：

IMMATICS BIOTECHNOLOGIES GMBH

发明人：TONI WEINSCHENK;CLAUDIA TRAUTWEIN;OLIVER SCHOOR;NORBERT HILF;HARPREET SINGH;STEFFEN WALTER

分类号：A61K39/00;A61K38/08;A61K38/16;A61P35/00

主分类号：A61K39/00

摘要：The present invention relates to peptides, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated cytotoxic T cell (CTL) peptide epitopes, alone or in combination with other tumor-associated peptides that serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses. The present invention relates to 25 novel peptide sequences and their variants derived from HLA class I and class II molecules of human tumor cells that can be used in vaccine compositions for eliciting anti-tumor immune responses.

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