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Combination Therapy for Cancer Using HSP27 Inhibitor and EGFR Tyrosine Kinase Inhibitors or Anti-Folates

申请公布号:US2015050285(A1)

申请号:US201314372972

申请日期:2013.02.01

申请公布日期:2015.02.19

申请人:
The University of British Columbia

发明人:Gleave Martin E.;Zoubeidi Amina;Kumano Masafumi

分类号:A61K39/395;A61K31/5377;A61K31/7088;A61K31/517

主分类号:A61K39/395

地址:Vancouver CA

摘要:Combination therapy for cancer makes use of HSP27 inhibitors and EGFR tyrosine kinase inhibitors or antifolates.

主权项:1. A method for treating cancer in an individual, comprising the steps of administering to the individual a therapeutically effective amount of a first active agent which is an inhibitor of Hsp27 activity, and administering to the individual therapeutically effective amount of a second active agent which is an inhibitor of EGFR tyrosine kinase activity.

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