IMMUNOCHROMATOGRAPHIC TEST STRIP AND DETECTION METHOD USING IMMUNOCHROMATOGRAPHY FOR DETECTING TARGET IN RED BLOOD CELL-CONTAINING SAMPLE,申请号EP20130768086-传众专利搜索

IMMUNOCHROMATOGRAPHIC TEST STRIP AND DETECTION METHOD USING IMMUNOCHROMATOGRAPHY FOR DETECTING TARGET IN RED BLOOD CELL-CONTAINING SAMPLE

申请公布号：EP2833142(A1)

申请号：EP20130768086

申请日期：2013.04.01

申请公布日期：2015.02.04

申请人：

SEKISUI MEDICAL CO., LTD.

发明人：YOSHIDA, MAYUMI;YAMAMOTO, MITSUAKI;YOKOKAWA, SHINYA;SHIMIZU, TOMO;KONO, KEIGO

分类号：G01N33/558

主分类号：G01N33/558

摘要：A problem to be solved by the present invention is to provide an immunochromatographic test strip and a detection method using immunochromatography avoiding aggregation of colloidal gold conjugates while red blood cells in whole blood are agglutinated and then separated and removed in the case of using polybrene as a blood-agglutinating agent and the colloidal gold conjugates as a detection reagent. To solve the problem, the present inventers reviewed a past reagent configuration itself from a completely different viewpoint rather than selecting type and amount of polyanions and, as a result of extensive study on each element, the inventers surprisingly found that aggregation of colloidal gold can be suppressed by using a certain buffer solution without using neutralization by polyanions.