METHODS AND DEVICES FOR CLASSIFYING AND MANAGING AUTOIMMUNE AND INFLAMMATORY CONDITIONS
申请公布号:US2015005186(A1)
申请号:US201414318556
申请日期:2014.06.27
申请公布日期:2015.01.01
发明人:HUANG Jing-Feng
分类号:G01N33/68
主分类号:G01N33/68
地址:San Diego CA US
摘要:Devices and methods useful for biomarker-based diagnosis of immunopathological mechanisms involved in autoimmune or inflammatory diseases are described.
主权项:1. A diagnostic method for differentiating underlying immunopathological mechanisms in patients having an autoimmune or inflammatory condition, comprising: a. contacting a biological sample, optionally a tear sample, obtained from a subject known to have or suspected of having autoimmune or inflammatory disease with a plurality of detection reagent species that each independently binds a biomarker species associated with an immunopathological mechanism involved in an autoimmune or inflammatory disease different from biomarker species bound by the other detection reagent species; and b. using the detection reagent species to determine if the biomarker species associated with the immunopathological mechanism in patients having an autoimmune or inflammatory disease are present in amounts indicative of an autoimmune or inflammatory condition, optionally, dry eye disease.
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