NUCLEAR TRANSPORT MODULATORS AND USES THEREOF

申请公布号：WO2014205389(A1)

申请号：WO2014US43479

申请日期：2014.06.20

申请公布日期：2014.12.24

申请人：

KARYOPHARM THERAPEUTICS INC.

发明人：BALOGLU, ERKAN;SHACHAM, SHARON;MCCAULEY, DILARA;KASHYAP, TRINAYAN;SENAPEDIS, WILLIAM;LANDESMAN, YOSEF;GOLAN, GALI;KALID, ORI;SHECHTER, SHARON

分类号：C07D249/08;A61K31/497;A61P35/00

主分类号：C07D249/08

摘要：The present invention relates to compounds of formula (I): and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising the compounds of formula (I) or their pharmaceutically acceptable salts, and methods of using said compounds, salts and compositions in the treatment of various disorders associated with CRM1 activity.

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