A BINDING MOLECULE ABLE TO NEUTRALIZE HEPATITIS B VIRUS

申请公布号：KR20140141460(A)

申请号：KR20140061977

申请日期：2014.05.23

申请公布日期：2014.12.10

申请人：

CELLTRION, INC.

发明人：YOON, JOON SUN;KIM, MAN SU;YI, KYE SOOK;LIM, BYUNG PIL;LEE, SEUNG EUN;HONG, SU HYEON;OH, JAE WOO;HUH, PHIL LIPP;CHANG, SHIN JAE;HONG, SEUNG SUH

分类号：C07K16/18;A61K39/42;G01N33/53

主分类号：C07K16/18

摘要：The present invention relates to a combination molecule having neutralization activity to hepatitis B virus by combining one or more selected from a group consisting of adw, adr, ayw, and ayr which are subtypes of hepatitis B virus surface antigen (HBsAg). The combination molecule of the present invention has excellent combination ability to HBsAg, accordingly can be combined on four main subtypes and shows neutralization effects, and shows wide combination abilities to various mutation antigen of HBsAg, thereby is very useful for preventing and treating hepatitis B.

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