Deformable transportable bioreactor chamber,申请号US201313945518-传众专利搜索

Deformable transportable bioreactor chamber

申请公布号：US8852933(B2)

申请号：US201313945518

申请日期：2013.07.18

申请公布日期：2014.10.07

申请人：

Illinois Tool Works Inc.

发明人：Porter Blaise Damian;Vilendrer Kent

分类号：C12N5/00;C12N5/02;C12M1/00;C12M1/12;C12M3/00;C12M1/34

主分类号：C12N5/00

代理机构：

McCarter & English, LLP

代理人：McCarter & English, LLP

地址：Glenview IL US

摘要：An apparatus and method is described for seeding and culturing cells on a sample. The apparatus includes a chamber in which the volume of the chamber may be adjusted without compromising the seal or sterility of the chamber. The apparatus enables the seeding of cells in a reduced volume and culturing of cells in an increased volume. Further, the apparatus enables application of forces, strains and torques to a sample during seeding, culturing or transportation of the sample.

主权项：1. A method of seeding and culturing a sample within a chamber, comprising the steps of: positioning a sample within a chamber capable of retaining a fluid and having a first volume and second reduced volume; seeding cells on the sample in the second reduced volume of the chamber; after said step of seeding cells, culturing the cells on the sample in the first volume of the chamber; engaging the sample between first and second grips in the first volume; and at least one of applying a linear force to the sample via the first and second grips and applying a torque to the sample via the first and second grips.