ALBUMIN BINDING ANTIBODIES AND BINDING FRAGMENTS THEREOF,申请号EP20120801467-传众专利搜索

ALBUMIN BINDING ANTIBODIES AND BINDING FRAGMENTS THEREOF

申请公布号：EP2776466(A1)

申请号：EP20120801467

申请日期：2012.11.09

申请公布日期：2014.09.17

申请人：

UCB PHARMA, S.A.

发明人：ADAMS, RALPH;BHATTA, PALLAVI;HEYWOOD, SAM PHILIP;HUMPHREYS, DAVID PAUL

分类号：C07K16/18;C07K16/28;C07K16/46

主分类号：C07K16/18

摘要：A serum albumin binding antibody or fragment thereof comprising a heavy chain variable domain having the sequence given in SEQ ID NO: 1 or SEQ ID NO:2 and/or comprising a light chain variable domain having the sequence given in SEQ ID NO:3 or SEQ ID NO:4, in particular comprising a heavy chain variable domain and a light chain variable domain having the sequence given in SEQ ID NO: 1 and SEQ ID NO:3 or a heavy chain variable domain and a light chain variable domain having the sequence given in SEQ ID NO: 2 and SEQ ID NO:4. The disclosure also extends to polynucleotides encoding the antibodies or fragments, vectors comprising same and host cells capable of expressing the polynucleotides. The disclosure further includes pharmaceutical compositions comprising the antibodies or fragments and therapeutic used of any one of the same.