METHODS AND DEVICES FOR ANALYZING SPECIES TO DETERMINE DISEASES
申请公布号:WO2014025961(A1)
申请号:WO2013US54059
申请日期:2013.08.08
申请公布日期:2014.02.13
发明人:CHAIT, ARNON;ZASLAVSKY, BORIS, Y.
分类号:G01N33/68
主分类号:G01N33/68
摘要:<p>The present invention, in some embodiments thereof, generally relates to methods and devices for determining the health status of a subject, e.g., whether the subject has a disease or other condition. In some embodiments, a plurality or mixture of species may be differentially solubilized in a single two-phase aqueous system, or other multi-phase aqueous system. The nature or degree of the solubilization of the species may be used to determine the health status of a subject. For example, some embodiments are directed to devices and methods for determining a disease or other condition as a function of the changes to the structure of two or more species. The species may be selected based on their differential solubility behavior in a two-phase or other multi-phase aqueous system. Preferential enrichment of the species concentrations in one of the phases, and/or the ratios of species in the phases may be determined, and in some cases compared to their respective values for healthy and/or diseased subjects to determine the health status of the subject.</p>