UREA COMPOUNDS AND THEIR USE AS ENZYME INHIBITORS,申请号CA20132879726-传众专利搜索

UREA COMPOUNDS AND THEIR USE AS ENZYME INHIBITORS

申请公布号：CA2879726(A1)

申请号：CA20132879726

申请日期：2013.07.24

申请公布日期：2014.01.30

申请人：

BIAL- PORTELA & CA, S.A.

发明人：ROSA, CARLA PATRICIA DA COSTA PEREIRA;GUSMAO DE NORONHA, RITA;KISS, LASZLO ERNO;SOARES DA SILVA, PATRICIO MANUEL VIEIRA ARAUJO;RUSSO, DOMENICO;WAHNON, JORGE BRUNO REIS;MATON, WILLIAM

分类号：C07D233/61;A61K31/4178;A61P31/00;C07C209/48;C07D233/88

主分类号：C07D233/61

摘要：A compound having the following structure: or a pharmaceutically acceptable salt or derivative thereof. The compound may be used in the treatment or prevention of a disorder selected from appetite regulation, obesity, metabolic disorders, cachexia, anorexia, pain, inflammation, neurotoxicity, neurotrauma, stroke, multiple sclerosis, spinal cord injury, Parkinson's disease, levodopa-induced dyskinesia, Huntington's disease, Gilles de la Tourette's syndrome, tardive dyskinesia, dystonia, amyotrophic lateral sclerosis, Alzheimer's disease, epilepsy, schizophrenia, anxiety, depression, insomnia, nausea, emesis, alcohol disorders, drug addictions such as opiates, nicotine, cocaine, alcohol and psychostimulants, hypertension, circulatory shock, myocardial reperfusion injury, atherosclerosis, asthma, glaucoma, retinopathy, cancer, inflammatory bowel disease, acute and chronic liver disease such as hepatitis and liver cirrhosis, arthritis and osteoporosis.