DONEPEZIL TRANSDERMAL PATCH,申请号EP20120734524-传众专利搜索

DONEPEZIL TRANSDERMAL PATCH

申请公布号：EP2663296(A1)

申请号：EP20120734524

申请日期：2012.01.12

申请公布日期：2013.11.20

申请人：

KO, SHAWN;TAIWAN BIOTECH CO., LTD.

发明人：YANG, KUO-HUA;YANG, CHIH-SHENG;LIN, HSUEN-YAU

分类号：A61K9/70;A61K31/445

主分类号：A61K9/70

摘要：The present invention relates to a donepezil transdermal patch comprising a backing layer and a pressure sensitive adhesive matrix layer, wherein the pressure sensitive adhesive matrix layer comprises donepezil free base and an acrylic pressure sensitive adhesive agent selected from the group consisting of a copolymer of 2-ethylhexyl acrylate and vinyl acetate and a copolymer of 2-ethylhexyl acrylate, vinyl acetate, and hydroxyl-containing monomers, and wherein 2-ethylhexyl acrylate is present in an amount of about 65% to about 75%, vinyl acetate is present in an amount of about 25% to about 35%, and the hydroxyl-containing monomers are in an amount of about 0% to about 10%, based on the total weight of the copolymer.