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PHARMACEUTICAL COMPOSITION FOR TREATMENT AND/OR PREVENTION OF CANCER

申请公布号:CA2865020(A1)

申请号:CA20132865020

申请日期:2013.02.21

申请公布日期:2013.08.29

申请人:
TORAY INDUSTRIES, INC.

发明人:KOBAYASHI, SHINICHI;OKANO, FUMIYOSHI;SAITO, TAKANORI

分类号:C07K16/30;A61K39/395;A61P35/00;C12N15/09;C12P21/08

主分类号:C07K16/30

摘要:The present invention discloses an antibody that targets a cancer antigen protein expressed specifically on the surface of cancer cells, and the application of the antibody in a treatment and/or preventative agent for said cancer. Specifically disclosed are: an antibody or a fragment thereof, said antibody being immunologically reactive with a partial polypeptide of CAPRIN-1 comprising the amino acid sequence represented by SEQ ID NO: 5 or an amino acid sequence having 80% or more sequence identity to the amino acid sequence represented by SEQ ID NO: 5; and a pharmaceutical composition for the treatment and/or prevention of cancer, said pharmaceutical composition being characterized by containing, as an active ingredient, the antibody or a fragment thereof.

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