NOVEL HETEROCYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS,申请号PT20050826587T-传众专利搜索

NOVEL HETEROCYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS

申请公布号：PT1831227(E)

申请号：PT20050826587T

申请日期：2005.12.15

申请公布日期：2013.08.23

申请人：

GLENMARK PHARMACEUTICALS S.A.

发明人：LAXMIKANT ATMARAM GHARAT;BALASUBRAMANIAN GOPALAN;NEELIMA KHAIRATKAR-JOSHI

分类号：C07D491/04;A61K31/343;A61K31/38;A61K31/407;A61P29/00;C07D471/04;C07D495/04

主分类号：C07D491/04

摘要：<p>The present invention relates to novel Phosphodiesterase type 4 (PDE4) inhibitors of the formula (1) and analogs, tautomers, enantiomers, diasteromers, regioisomers, stereoisomers, polymorphs, pharmaceutically acceptable salts, appropriate N-oxides, pharmaceutically acceptable solvates thereof and the pharmaceutical compositions containing them which are useful in the treatment of allergic and inflammatory diseases including asthma, chronic bronchitis, atopic dermatitis, urticaria, allergic rhinitis, allergic conjunctivitis, vernal conjunctivitis, eosinophilic granuloma, psoriasis, rheumatoid arthritis, septic shock, ulcerative colitis, Crohn's disease, reperfusion injury of the myocardium and reperfusion injury of the brain, chronic glomerulonephritis, endotoxic shock and adult respiratory distress syndrome.</p>