A METHOD FOR PRODUCING STABLE, AMORPHOUS HYBRID NANOPARTICLES COMPRISING AT LEAST ONE PROTEIN KINASE INHIBITOR AND AT LEAST ONE POLYMERIC STABILIZING AND MATRIX-FORMING COMPONENT,申请号CA20132860973-传众专利搜索

A METHOD FOR PRODUCING STABLE, AMORPHOUS HYBRID NANOPARTICLES COMPRISING AT LEAST ONE PROTEIN KINASE INHIBITOR AND AT LEAST ONE POLYMERIC STABILIZING AND MATRIX-FORMING COMPONENT

申请公布号：CA2860973(A1)

申请号：CA20132860973

申请日期：2013.01.11

申请公布日期：2013.07.18

申请人：

XSPRAY MICROPARTICLES AB

发明人：BRISANDER, MAGNUS;DEMIRBUKER, MUSTAFA;JESSON, GERALD;MALMSTEN, MARTIN;DERAND, HELENE

分类号：A61K9/14;A61K31/506;A61K31/517;A61K47/32;A61K47/34;A61K47/38

主分类号：A61K9/14

摘要：The present invention relates to the field of methods for providing components of pharmaceutical compositions comprising poorly water-soluble drugs. In particular the present invention relates to methods for providing stable, amorphous hybrid nanoparticles, comprising at least one protein kinase inhibitor and at least one polymeric stabilizing and matrix-forming component, useful in pharmaceutical compositions.