A PHARMACEUTICAL COMPOSITION COMPRISING STABLE, AMORPHOUS HYBRID NANOPRATICLES OF AT LEAST ONE PROTEIN KINASE INHIBITOR AND AT LEAST ONE POLYMERIC STABILIZING AND MATRIX-FORMING COMPONENT
申请公布号:CA2860932(A1)
申请号:CA20132860932
申请日期:2013.01.11
申请公布日期:2013.07.18
发明人:BRISANDER, MAGNUS;DEMIRBUKER, MUSTAFA;JESSON, GERALD;MALMSTEN, MARTIN;DERAND, HELENE
分类号:A61K9/51;A61K9/14;A61K31/506;A61K31/517;A61K47/32;A61K47/34;A61K47/38;A61P35/00
主分类号:A61K9/51
摘要:The present invention relates to the field of methods for providing pharmaceutical compositions comprising poorly water-soluble drugs. In particular the present invention relates to compositions comprising stable, amorphous hybrid nanoparticles, comprising at least one protein kinase inhibitor and at least one polymeric stabilizing and matrix-forming component, useful in pharmaceutical compositions and in therapy.
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