CARBON MONOXIDE RELEASING MOLECULES AND USES THEREOF,申请号WO2012US34264-传众专利搜索

CARBON MONOXIDE RELEASING MOLECULES AND USES THEREOF

申请公布号：WO2012145520(A3)

申请号：WO2012US34264

申请日期：2012.04.19

申请公布日期：2012.12.27

申请人：

ALFAMA, INC.;BLAETTLER, WALTER, ANTON;ROMAO, CARLOS, J. R. C.;RODRIGUES, SANDRA, SOFIA PEREIRA;KROMER, LUKAS, ADRIAN;OTTERBEIN, LEO, EDMOND;GALLO, DAVID, JOHN

发明人：BLAETTLER, WALTER, ANTON;ROMAO, CARLOS, J. R. C.;RODRIGUES, SANDRA, SOFIA PEREIRA;KROMER, LUKAS, ADRIAN;OTTERBEIN, LEO, EDMOND;GALLO, DAVID, JOHN

分类号：A61K31/555;A61K33/00

主分类号：A61K31/555

摘要：Provided herein are novel carbon-monoxide releasing molecules (CO-RMs) of the Formula (I): and esters, amides, salts, solvates and hydrates thereof; wherein R1 and R2 are as described herein. Also provided are pharmaceutical compositions comprising these compounds, methods of their preparation, and their use in the treatment of liver disease and inflammation.